Has your dog reacted badly to 'Cytopoint' injection (new anti-itch shot)

Mark Q

New member
Joined
Dec 10, 2020
My dog MAX was itching a lot . I took him into the local vet. they gave him a cytopoint injection he became very lethargic and Short of breath . I rushed him to the Vet hospital he was diagnosed with AIHA Autoimmune hemolytic anemia. He received 4 blood transfusions with out response.
We were about to euthanize him but we decided to give him one more blood transfusion. His blood count slowly returned to normal after several weeks. This was in April of this year. He is almost back to normal but he has to have medicine daily. Cytopoint needs a warning label.
 

JessiesDad

New member
Joined
Jan 21, 2021
My dog had 'Cytopoint' injection 3 weeks ago (new anti-itch med) and her existing back/pain issues seemed to have increased. Due to get 2nd injection in 3 days......Has anyone else experienced similar?? Hesitating to get 2nd shot.
My shih Tzu mix was brought to our Vet for skin allergies on Sept 13, 2017, that he contracted about a year ago and the allergies came back this summer with a little more intensity. He had some itchy scaly spots on his skin. His name was Georgie. Georgie was 13 years old and in very good health with no underlying diseases or illnesses. As far as we knew and as far as we observed Georgie was happy and running around the day we brought him in for skin allergies.

Last year in 2016, I decided to just put Benadryl cream on his skin and eventually the allergies subsided. This year, because the itching was a bit more intense we decided along with the vet to give him the CytoPoint Injection to help him stop itching. Two days after the injection, Georgie began to bleed internally. His antibodies began to attack his red blood cells and Platelets.

Georgie died 7 days after the CytoPoint injection and after 3 blood transfusions. CytoPoint killed my dog. This is a warning to all Pet owners. Cytopoint has not been on the market long, only 8-9 months, with ONE case study. We unfortunately researched everything about the company Zoetis and CytoPoint after the death of my dog.

Please DO NOT have CYTOPOINT administered/injected into your Dog for allergies or itchy skin. CytoPoint is a Biologic with Antibodies that are to program how cells send messages to the brain about itching. Georgie was injected with these Antibodies, where the antibodies turned against his body attacking red blood cells and platelets. My family is in pursuit to go after Zoetis for compensation for the $5,000 of Emergency Blood Transfusions that we incurred. Please head this warning and share with anyone you think may be considering CytoPoint for their Dog.
Sorry for your loss. My dog has had this shot recently (twice), and, within a week both times, her face swelled up, she was lethargic, didnt eat, didnt want to play, and threw up a lot. We had a bunch of tests, to no avail, so I finally put it together. Shame on this company and the FDA.
 

R Jill F

New member
Joined
Feb 6, 2021
I am so very sorry. We had a very similar situation with our shih tzu LOUIE. We took him to the vet (in Port Hueneme, CA) for constant itching. He was given the very expensive shot CYTOPOINT. The first shot seemed to help. It was recommended to return once a month to get another shot. I DID NOT come back for 3 months (COST) and he seemed ok.

Then he went back to the vet, my husband took him and he was given another shot. Still ok, but went back with my husband a month later to update his rabies shot and for an ear infection. GIVEN A 3rd shot of CYTOPOINT and that’s where we almost lost our dog. I stopped any further Cytopoint at this point.

He was completely lethargic after that. He didn’t bounce when he walked and he went downhill from there. Had blood work up done and his red blood count was at 11. He was put in prednisone. The vet would NOT acknowledge that the CYTOPOINT had anything to do with it. Vet said he had an auto-immune issue.

BUT Cytopoint DOES something with the immune response targeting what ever makes a dog itch and lowering that response! In MY OPINION it messed up his ability to produce Red Blood cells. Our vet said when he can’t walk to go to the bathroom it is time to put him down. I CHANGED VETS!!!!! went to a Holistic vet who placed him on another immune suppressant.

Ultimately he had to get TWO BLOOD TRAN$FU$ION$ and still would not produce RED BLOOD CELLS. They kept dying off. He was on two immune suppressants at that time. The ONLY SOLUTION was that he was so miserable on all the medication the vets had given that I TOOK HIM OFF ALL MEDS! Guess what......HE IMPROVED!!! Saw improvement within days and had blood checked about a month later.

No longer anemic! Holding his own with pink tongue. Bouncing as normal, scratches some but I don’t care. That medication is horrific And my dog should never have been given it every month. Vets make money by giving shots and medication and I have been told animal meds are not researched as much human medications are.

So it’s trial and error with OUR PETS. DON’T BUY INTO CYTOPOINT AND RESEARCH ANY MED THAT VETS ARE PUSHING. I really lost faith in them. Good luck! 👍🏼 💜 and the Vets don’t want to acknowledge or even consider that this drug is bad. Why is that I wonder? Again, I feel for you. It is really sad.
 

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Alpha1

Pack Leader and Lover
Joined
Mar 28, 2012
Location
USA
Hi @R Jill F, welcome! Good to hear your dog is doing okay and survived these shots. My dog does have seasonal allergies and itching, I heard about the Cytopoint shot and would never let them give it to my dog, but they never suggested it. They did give me a script for Apoquel, but after doing my own research and seeing that it suppressed the immune system, I decided not to give him those pills either.

He's gotten better as years go by, I give him a bath with Zymox shampoo and conditioner to ease the itching during the spring to fall season. I've also given him Dynovite supplement and Colostrum supplement during these times. Don't know exactly what is helping him improve, may be a combination of everything.

Also make sure to brush my boy daily throughout the year, but especially during allergy season, he goes to parks daily that have an assortment of weeds and grasses that likely have pollens which affect his condition, plus behind our back fence is a large open field with weeds and bushes that make the matter worse. I also vacuum at home more often to get as much dust, dirt and pollens off the carpet. Giving them some Krill Oil, Fish Oil or Coconut Oil a few times a week also seems to help make the skin not so dry and itchy.

Louie is very cute, hope he stays healthy! 🧡
 

Starshine

New member
Joined
Feb 17, 2021
instead of mixing kibble with the raw use ground up green beans, not canned, frozen or fresh, this will add bulk to his diet but very few calories and he will loose weight. Feeding raw he should be getting two or three percent of his body weight divided into two meals. Don't forget to add the right additives to a raw diet, get some honest kitchen add 1/4 cup mixed with equal warm water, let it sit and mix with the raw food this is all the "greens" he needs in his diet, Also add 1 tablespoon of missing ; link for skin and coat, this is all the vitamins and minerals he might be missing in his diet.

get some unscented baby wipes and wipe his feet, belly and face every time he comes inside. this will get off the i irritants he's getting from outside. Also get a bottle of liquid colloidial silver , mix it half and half with water and put it in a spray bottle and spray his body a couple of times a day.

My nephew has a white pitbull and this is what I told him to do and no more itching.


Wow thanks so much. I already have colloidial silver at home anyways! I've been trying to see more natural holistic approach we have a specialist appointment but I am not certain their approach will be without more drugs. So It seems as with anything else in animal or human medical world it's up to us to do further research and gather information as much as possible. No one else is there to look out for us and our animals. Unfortunately.

Thanks for your help
 

shipra.sethi

New member
Joined
May 15, 2019
Just updating you guys. Our Coco who had developed strange symptoms after Cytopoint (similar to a stroke but eventually diagnosed as IMPA) Passed away last December 2020. He was on steroids for almost a year to manage these symptoms, which ended up causing a gastric perforation, that took him away from us forever.
He was our only baby as I have had three miscarriages in last two years.. we spent all of our energy/money/time in saving him... so many specialists... we had found a good internist but she left the practice due to Covid that’s why his GI bleed couldn’t get diagnosed in time..
I am in medical profession and I hate myself for ever having him take that shot... I hate Vets who put money over lives...
Please do not give Cytopoint to your dogs
 

sagia038

New member
Joined
May 31, 2021
My dog received cytopoint he has dermatitis he broke out in hives all over his body worse than the allergy he has it’s oozing we had to shave his whole body just so it would dry out i gave him 2-3 that usually last 2 months i will never give it to him again he has totally suffered from it !!!
 

littlegrays

New member
Joined
Jun 1, 2021
Location
Orlando, FL
First, I am so sorry to everyone who has experienced the horrors of this injection and I am terribly sorry to those who have lost their fur babies. My heart goes out to all of you!

I wanted to share in case someone else was experiencing something similar. It is a long post, but I wanted to lay it all out there in detail. Numerous vets have brushed us off when we mentioned a possible side effect to Cytopoint.

Our Shih-Tzu turned 15 in April. She is our baby, my heart dog and our world. In November 2020 we took her to the vet because she was licking herself non-stop and she created little hot spots on her belly. Due to COVID protocols, we sat in the car while the vet examined her. Our vet didn’t even ask and just gave her the Cytopoint injection. We were so upset and I would’ve never allowed it.

A week after the injection, she woke us up in the middle of the night coughing, then made this wailing cry, fainted/was unresponsive and limp. She came to after a few seconds, which felt like an eternity. After coming to she urinated. In December she had a few of these episodes, identical to the one in November starting with the cough, ending in urination.

Two episodes looked like seizures because she started twitching in her face and her tongue came out of her mouth and she was breathing heavily. Through all of these episodes, I thought we were going to lose her and she wouldn’t come out of it. We rushed her to the emergency vet numerous times, took her to specialists – neuro and cardio. The neuro put her on Keppra because he believed it was seizures.

We weaned her off Keppra because we didn’t think it was truly seizures. We learned about syncope and saw some YouTube videos and that is exactly what it looked like.

Fast-forward to now about 6 months post-injection, she has had a few more fainting episodes. They have been milder than the ones in December. Her appetite has been awful since injection. She was a dog who would eat anything and everything, even medicine without pill pockets. She has been turning away chicken, eggs, beef, sardines. We have been giving her daily probiotics, multivitamins (were using Dr. Dobias’ two powders) and as much love as we possibly can give.

She has had very mild stable mitral valve disease for 7 years and it appears it has gotten worse recently. Her echo in November looked the same as previous years. Middle of April at her follow-up echo- her heart is now worse, she also now has pulmonary hypertension (on Sildenafil) and on Theophylline because they think she has vasovagal syncope.

While what we're experiencing isn’t exactly what others have experienced after the injection, she has become sensitive to things she never was sensitive to and had numerous infections – a bunch of UTI’s that required multiple rounds of antibiotics to clear and ear infections. Her allergies have been out of control since the injection too. Her breathing has also been abnormal like she hasn’t been taking full deep breaths.

It is just too coincidental for us. All of a sudden her stable heart issue worsened post-injection and having issues she’s never had before. I understand the heart issues are progressive, but I can't look past the infections and timeline, it just all seems related to this horrible injection.

Besides her mitral valve disease, we had a healthy girl who people didn’t believe was as old as she was, even vets were shocked at how good she looked. We have done as much research as we could about Cytopoint and we found that the Il-31 receptor is an inflammatory cytokine that also plays a role in allergic diseases, asthma and bronchial tissue. I can only imagine the amount of inflammation and autoimmunity this injection is doing.

As others here have stated, this isn’t a side effect-free, super safe wonder drug like vets claim it is. This shot is a killer and can cause so many issues that leave us pet parents feeling so helpless! Our babies don’t deserve this!!
 

TTouch

Member
Joined
Apr 20, 2021
PLEASE report this 'Vet prescribed medication' if you have used it and had ANY negative results IN WRITING to the VET who gave it and to the animal medications board of your country as without people REPORTING NOTHING WILL CHANGE and more pets and owners will continue to pay for it, get their pet vaccinated with it and have more issues

US https://www.fda.gov/animal-veterinary/product-safety-information/veterinary-medication-errors
UK https://www.gov.uk/report-veterinary-medicine-problem

If another country then google "animal medication problems/issues" to find your countries reporting website, it take minutes and YOU are the experts who know the affects
 

canismajor

New member
Joined
Jun 2, 2021
Greetings!

Two of our dogs were suffering with seasonal allergies, mostly severe itching and irritations leading to ear infections.

Three years ago, our vet recommended Cytopoint injections for both.

As of this year, they each have had Cytopoint injections once a year for three years running, and we have observed no negative side effects. The Dalmatian mix gets an 80mg dose, while the Bassett Hound gets 60mg.

The injections have been such a relief, for us and the dogs. It's so hard to see them suffer, while we tried myriad things to help them. The first Cytopoint shot was almost miraculous for us. Total relief within a day, lasting through autumn. Same with the subsequent shots.

I'm sad to hear of the folks with a different experience. As with humans, it difficult to tell how an individual will react to a vaccine or any medication. I hope you all find ways to help your dogs find comfort.

I realize this may sounds a bit like an advertisement, so I feel the need to say that we are not connected to the makers of Cytopoint in any way, other than as users/customers. We are simply satisfied with the results and have observed, with no negative effects from the shots over the course of three years now.

Best to you all,

cm
 

Alpha1

Pack Leader and Lover
Joined
Mar 28, 2012
Location
USA
Just about to take my dog to the Vet for itching. So glad I read this first.
My dog is just starting with his seasonal allergy itching, I will never let them give him this cytopoint injection, just from all I've learned here. They gave me a prescription a few years ago for allergy pills, but after researching the side effects of those online, and learning they suppress the immune system, I threw them out and didn't even give him one.

I keep him trimmed in a short to medium cut (do it myself), give him a daily brushing with a medium bristle brush, give him baths when needed (not too often) with Zymox shampoo and leave in conditioner, keep my carpets well vacuumed, etc.

Good luck with your dog. We have a big yard with some weeds, an open space area behind our chain link fence with a lot of weeds there, and walk him daily in the park that has weeds. I recommend trying to deal with it more naturally, the vets have go-to meds and injections that they are encouraged to use, but we're all better off the less prescription drugs we have in our systems. Welcome.
 

Alpha1

Pack Leader and Lover
Joined
Mar 28, 2012
Location
USA
Greetings!

Two of our dogs were suffering with seasonal allergies, mostly severe itching and irritations leading to ear infections.

Three years ago, our vet recommended Cytopoint injections for both.

As of this year, they each have had Cytopoint injections once a year for three years running, and we have observed no negative side effects. The Dalmatian mix gets an 80mg dose, while the Bassett Hound gets 60mg.

The injections have been such a relief, for us and the dogs. It's so hard to see them suffer, while we tried myriad things to help them. The first Cytopoint shot was almost miraculous for us. Total relief within a day, lasting through autumn. Same with the subsequent shots.

I'm sad to hear of the folks with a different experience. As with humans, it difficult to tell how an individual will react to a vaccine or any medication. I hope you all find ways to help your dogs find comfort.

I realize this may sounds a bit like an advertisement, so I feel the need to say that we are not connected to the makers of Cytopoint in any way, other than as users/customers. We are simply satisfied with the results and have observed, with no negative effects from the shots over the course of three years now.

Best to you all,

cm
Thanks for sharing your experience, I'm glad to hear that your dogs have not been negatively affected, but I imagine you are the exception, not the rule for this injection. Personally, I will not take the chance with my boy.
 

TTouch

Member
Joined
Apr 20, 2021
I personally see this as a huge mine field.

Dogs have always 'itched' but as they now live indoors, in centrally heated homes 24/7, so 'we' see the itching whereas before 'we' didn't. However I think we as a society need to take responsibility for causing more 'itching' issues.

It is important to know why they are itching and what if anything can be done to help... Environmental, hormonal, genetic, seasonal, food or parsites and 'we' owners demand/want 'quick fixes' and vets like to provide that quick fix in more chemical medications and selling the kibble they stock..... and over the years vets have encouraged this thought process along with pet food manufacturers that they are the 'be all and end all' to all issues when in reality they are only highly trained and qualified MEDICAL professionals unless they have taken additional qualifications and most haven't and don't.

Itchy skin is an uncomfortable, irritating sensation that makes them want to scratch known as pruritus, itchy skin is often caused by dry skin and centrally heated houses don't help, wanting our dog to be 'smelling nice' and so using nice smelly shampoos, so the perfumes in them can cause dry skin as does bathing too frequently as it strips their natural oils and that dries their skin and a dogs Ph is different to human Ph so human products will also dry their skin.

'We' are obsessed with cleaning and use a variety of commercial products, from floor cleaners, bleach, washing liquids/conditioners, fabric 'deodorisors' 'air freshoners, scented candles...so dogs ( and cats) can lay on their nice cleaned ( by chemicals) bed, walk on floors and carpets that we have used chemicals on which is picked up on their pads and/or pick up chemicals via their nose going into their blood system and affects their immune system, so it fights those and not the job it should do to keep them naturally healthy and our cars, factory's and homes pump out chemicals into the air

If it is a genetic issue there is nothing at all you can do to change that you can only at best manage it, as it is down to poor breeding of unsuitable dogs with genetic skin issues and/or poor immune systems.

We obviously don't want or need fleas in the home and because they live inside really there is no 'flea season' it can be an all year round issue to keep them 'flea free' so for the majority of owners chemical treatments are a monthly norm but those chemical are poisons that goes into the dogs blood stream that kills and/or is a 'flea' contraceptive.

'We' feed them inappropriate food, they are meat eaters and ideally wild prey as the meat has not been bleached or injected with brines and colours or when alive fed growth hormones or given anti biotics, dogs are not cereal, sugar eaters, they don't need them or 'added colours' in food like 'ash' and 'carbon' made by burning wood/sawdust/rotting veg/paper it is all for and to sell to humans and other chemical shades made so it appears as though the red kibble is red meat, yellow kibble is chicken, and green kibble is vegetables and greens.. its not! Each kibble piece is EXACTLY the same, the sludge/dough is just split and either a dye or lake is added and the same goes for commercial treats.
Each and everything we or our dog takes in any medication does also affect the immune system, we can all 'do something' to remove some issues, whether that be cleaning using steam or things like white vinegar, the food/treats we choose to feed , using natural flea/wormers that work and boost the immune system, not over vaccinating our pets and having titers tests instead so we KNOW if they need the vaccination or not , groom more rather than bathe and there are things that society/businesses could/can do like stop using chemical fertilizers, growth hormones, pumping waste into our air.......
.....and I KNOW there is no easy answer and I also KNOW there is no quick fix, my heart goes out to people who have lost their dogs to 'new' quick fix medication or their dogs are now suffering other health issues because of it, it is frightening and I LOVE that people have shared their own results as this particular drug only on the market from 2017 is still very much in testing and it is being tested in the field on your dogs
Personally, I will not take the chance with my boy.
I totally agree, my dogs will also not be used as a 'guinea pig'
 
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Lorraine O.

New member
Joined
Sep 16, 2021
My dog Daisy (age 10) passed away this week from Kidney Failure. I suspect her kidney disease was linked to Cytopoint. She suffered from severe seasonal allergies and would lick and scratch herself till raw and infected. She has seen an allergist for about 4 years and received regular allergy vaccines year round that didn't do much good. She was on Apoquel for the first 2 years, but I had concerns about the effects of Apoquel. Last year in 2020 the allergist suggested Cytopoint. Switched to that in early summer 2020. No routine blood work required. Late summer 2020, her kidney values were elevated. Started her on prescription KD diet. She went back on Cytopoint this year early May. At that point, her kidney values were even higher and she had lost 2/3 of her kidney function. She received 3 shots of Cytopoint this year and ended up with Kidney Failure. Only major change is Cytopoint since 2020. No indication of Kidney side effects from Cytopoint. I asked the allergist to report this suspected link. I think more research needs to be done on Cytopoint and at least regular blood work be required similar to Apoquel requirements.
 

Concerned Friend

New member
Joined
Oct 27, 2021
My lady friend, took her dog Moe 11yrs (not sure of exact age saved pet) for a nail trimming and mentioned doggie belly was pink, next thing my friend knew the Vet (first time seeing Moe) gave her doggie a shot, my friend thought it was a steroid or benydryl shot) it turned out to be Cytopoint (brand name) made by Zoetis, drug name is lokivetmab. Moe stopped eating same day, had diarrhea and when forced to eat could not keep food in threw up each time. Moe died 6 days after this shot. Looking at other reports of this drug used on doggies shows this drug is not safe at all and the vet claims the drug is safe. The vet should have known this drug was not safe especially for older dogs. What I also seen is pet owners returned to their vets and incurred all kinds of bills expensive ER and medical procedures to save the dogs and you have to think was it all a plan to make money and hopefully save dog through expensive blood transfusions or other drugs and ER stays. My lady friend is devastated and reason I am posting in hopes to save others the expensive (possibly planned) vet fees for giving shot then administering SAVE pet procedures. Who can you trust. Research don't just say yes to Doctors, they are out for the money it appears. $105.00 for the shot Cytopoint that killed her doggie. Horrible makes you think about the jab for humans and who to believe.
 

GEOWD3

New member
Joined
Nov 15, 2021
My dachshund almost three years old. Developed allergies last May. Vet gave him Cytopoint shot, which helped. Three weeks later he had a seizure. Vet assured me it was not related to Cytopoint. In October he, again started in with itchy scratching. Vet gave him another Cytopoint shot. Yesterday he had another seizure, again about three weeks since shot. Coincidence? I have my doubts now about Cytopoint. I have call into vet. In the two plus years that I had him before the shot, he never had a seizure
 

TTouch

Member
Joined
Apr 20, 2021
Make sure you report this to your countries Animal Medications Licensing Authority as they are the department that license any new medications to the market and they are the department that can suspend/cancel the license of this dangerous animal medication that is causing deaths and serious medical issues for too many animals being given it as Vets only go by the fact it has a license as 'safe' to use
 

Yukon’s Mom

New member
Joined
Dec 18, 2021
Hi I’m new to this, but my 9 year old GSD got his first shot of Cytopoint yesterday, 100mg. He has had Pannus since he was 2, but it has been totally controlled. A few years ago he developed allergies and took Apiquel until a year ago and sometimes prednisone. He was tested and found to be allergic to all sorts of plants that grow on trails etc. where he hikes. Based on the tests, he was prescribed injections for his allergies, and 2 years after being on that protocol, he still gets yeast infections, has lost a lot of hair from his legs and feet, and scratches a lot. He was frisky when I brought him more yesterday; he ate his dinner and seemed normal. When I got up this morning I found he had thrown up in the night. He has been on my bed all morning and wouldn’t get up to go out or eat. I hand fed him a little bit. He is very lethargic. After reading all of this, I’m worried. My vet assured me this was safe!
 


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